From Forbes.com
[Note: I am not a personal fan of coffee. I had a few cups over to decades ago and haven't touched it since. I am still a happy person B"H...:-)].
Drinking a cup of coffee first thing in the morning blunts the energy-boosting effects of caffeine and may lead to increased tolerance of the stimulant. This counterintuitive fact is explained in by Ryoko Iwata [what a shayne yiddishe name!!:-)], "a Japanese coffee-lover living in Seattle" on her appropriately titled blog, I Love Coffee. Iwata based her post on research gathered by Steven Miller, a Ph.D. candidate at the Uniformed Services University of the Health Sciences in Bethesda.
Everybody is different, of course, but we are all guided by the 24-hour hormonal cycle referred to as the circadian clock. These basic rhythms are preprogrammed into us genetically and although we can mess with our cycles through lifestyle habits, the major factor in their regulation is sunlight. One of the things that this clock controls in humans is the release of the a hormone called cortisol which makes us feel alert and awake.
Here’s the thing. The peak production of cortisol occurs between 8–9 am (under normal circumstances.) This means that at the time that many people are having their first cup of coffee on the way to work, their bodies are actually “naturally caffeinating” the most effectively! According to Iwata, the effects of caffeine consumption at times of peak cortisol levels actually diminishes the effectiveness of the additional stimulation. Worse still, “By consuming caffeine when it is not needed, your body will build a faster tolerance to it, and the buzz you get will greatly diminish.”
Cortisol is also considered a stress-related hormone and consumption of caffeine has been shown to increase the production of cortisol when timed at periods of peak cortisol levels. An increased tolerance for caffeine can therefore lead to heightened cortisol levels which can disturb circadian rhythms and have other deleterious effects on your health.
The times of peak cortisol levels in most people are between 8-9 am, 12-1 pm and 5:30-6:30 pm. Therefore, timing your “coffee breaks” (an apt term) between 9:30-11:30 and 1:30 and 5:00 takes advantage of the dips in your cortisol levels when you need a boost the most.