Non-ruchani people have their ego bound up in their job, money, social status or other silliness.
Ruchani people have their ego bound up in how well and how much they learn, which famous rabbonim they are close to and how many mitzvos they do.
Emes-dikke ruchani people, true Bnei and Bnos Aliyah - eradicate their ego and realize that it's not about them at all.
The gemara says that there is no room for Hashem when people are full of themselves.
Simman la-davar: E.G.O. roshei teivos Edge G-d Out.